Endocrinology2 UKMLA questions
Type 1 diabetes mellitus — UKMLA Revision Notes
Type 1 diabetes mellitus is an important clinical condition in Endocrinology that is tested in the UKMLA Applied Knowledge Test (AKT). Medical students and doctors preparing for the UKMLA or PLAB 1 must understand the pathophysiology, clinical presentation, investigations, and evidence-based management of Type 1 diabetes mellitus as outlined in current NICE guidelines.
Key Facts
- Type 1 diabetes mellitus is a key condition on the GMC UKMLA Content Map
- Commonly tested in the Endocrinology section of the UKMLA Applied Knowledge Test
- Understand the pathophysiology, clinical features, investigations, and management
- NICE guidelines provide the evidence base for management decisions
- Consider differential diagnoses and red flag symptoms in clinical scenarios
Investigations
- TFTs (TSH, T4, T3)
- Fasting glucose/HbA1c
- Cortisol (9am)
- Pituitary MRI
- Bone profile
- Urine/serum osmolality
Management
- Hormone replacement/suppression as indicated
- Lifestyle modification (diet, exercise)
- Monitor for complications
- Endocrinology outpatient follow-up
- Patient education and self-monitoring
- Surgical referral if indicated