Stevens-Johnson syndrome — UKMLA Revision Notes

Stevens-Johnson syndrome is an important clinical condition in Dermatology that is tested in the UKMLA Applied Knowledge Test (AKT). Medical students and doctors preparing for the UKMLA or PLAB 1 must understand the pathophysiology, clinical presentation, investigations, and evidence-based management of Stevens-Johnson syndrome as outlined in current NICE guidelines.

Key Facts

Stevens-Johnson syndrome is a key condition on the GMC UKMLA Content Map
Commonly tested in the Dermatology section of the UKMLA Applied Knowledge Test
Understand the pathophysiology, clinical features, investigations, and management
NICE guidelines provide the evidence base for management decisions
Consider differential diagnoses and red flag symptoms in clinical scenarios

Investigations

Clinical examination
Skin biopsy
Patch testing
Wood's lamp
Dermoscopy
Swab for MC&S

Management

Topical treatments (emollients, corticosteroids, antifungals)
Systemic therapy if severe
Sun protection advice
Dermatology outpatient follow-up
Patch testing for contact dermatitis
Biopsy if diagnosis uncertain

Practice 2+ Stevens-Johnson syndrome Questions

Test your knowledge with SBA questions on Stevens-Johnson syndrome and all 430 UKMLA Content Map conditions. Instant feedback, NICE guideline explanations, and spaced repetition included.